c-Cbl–deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action
J. Clin. Invest. Juan C. Molero, et al. 114:1326 doi:10.1172/JCI21480 [Go to this article.]

Figure 2
Glucose metabolism in overnight-fasted WT and c-Cbl–deficient mice in vivo. (A) Glucose tolerance test (2 g/kg) in 16- to 18-week-old mice. (B) Circulating insulin levels during the glucose tolerance test. (C) Percentage change in blood glucose during an insulin tolerance test (0.5 U/kg). Histograms on the right show the area under the curve. Data represent the mean ± SEM of 10–12 animals per group. *P < 0.01; **P < 0.001.