Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen
J. Clin. Invest. Cassian Sitaru, et al. 115:870 doi:10.1172/JCI21386 [
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Figure 7The extent of cutaneous disease in the mice depends on the injected amount of immune rabbit IgG. The extent of disease was scored as described in Methods and in Table
2. Means of individual clinical scores (n = 4) are shown before the first injection as well as 4, 8, and 12 days later. Significantly more extensive disease was induced in mice injected with 7.5 mg or 15 mg of immune IgG compared with mice treated with 3.75 mg of IgG.
