Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen
J. Clin. Invest. Cassian Sitaru, et al. 115:870 doi:10.1172/JCI21386 [
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Figure 6Experimentally induced splits localize below the lamina densa. Electron microscopic examination of a lesional skin biopsy from a diseased mouse demonstrates that the blister roof contains the lamina densa (LD) bordered by basal keratinocytes (BK) with hemidesmosomes (HD) (arrows). Dermal connective tissue represents the blister floor (magnification, ×11,000; inset: magnification, ×44,000).
