Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen
J. Clin. Invest. Cassian Sitaru, et al. 115:870 doi:10.1172/JCI21386 [Go to this article.]

Figure 5
By light microscopy, antibodies specific to type VII collagen cause subepidermal splits. (A) Histologic examination of skin biopsies from a diseased mouse reveals extensive subepidermal cleavage (magnification, ×200). (B) The inflammatory infiltrate is dominated by neutrophils (magnification, ×400). (C) No specific histologic alterations are found in the skin of a mouse treated with control IgG (magnification, ×200).