Steven G. Deeks, Bruce D. Walker
J Clin Invest.
2004;
113(6):808–810
doi:10.1172/JCI21318
This article Copyright © 2004, The American Society for Clinical Investigation
Abstract
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potent antigen-specific T cell response to HIV infection can contribute to the control of viral replication and is therefore beneficial to the host. However, HIV-mediated increases in generalized T cell activation also appear to accelerate both viral replication and CD4+ T cell depletion. A new study in the JCI attempts to experimentally distinguish the beneficial versus harmful aspects of this immune response.
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