Bateman domains and adenosine derivatives form a binding contract
J. Clin. Invest. Bruce E. Kemp, et al. 113:182 doi:10.1172/JCI20846 [
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Figure 1Pairs of CBS sequences within a protein fold into Bateman domains that bind adenosyl compounds and that mediate the allosteric control of their parent proteins. Shown is the surface-modeled Bateman domain formed by the CBS-1 and CBS-2 sequences of the AMPK γ1 subunit with AMP present in the central binding pocket (
4). AdoMet,
S-adenosyl methionine.