Mice lacking the syndecan-3 gene are resistant to diet-induced obesity
J. Clin. Invest. April D. Strader, et al. 114:1354 doi:10.1172/JCI20631 [
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Figure 1Body weight gain of
syndecan-3–/– and wild-type mice on LF (11% fat) and HF (41% fat) diets. (
A and
B) Male (
A) and female (
B)
syndecan-3–/– (–/–) and wild-type (+/+) mice (
n = 6–10 in each group) were given ad libitum access to diets for 14 weeks (*
P < 0.05, repeated-measures two-way ANOVA; gene-diet-sex interaction, –df = (1, 50); F = 7.72;
P = 0.007).
