Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension
J. Clin. Invest. José M. Fernández-Fernández, et al. 113:1032 doi:10.1172/JCI20347 [Go to this article.]

Figure 4
Plot of V_1/2 versus Ca²⁺ concentration. (A) V_1/2 versus Ca²⁺ concentration obtained for α+β_1WT (n = 13) and α+β_1E65K (n = 15). (B) V_1/2 versus Ca²⁺ concentration for α+β_1WT and α+β_1WT+β_1E65K (n = 6). (C) V_1/2 versus Ca²⁺ concentration for α (n = 3). Data are shown as mean ± SEM. Differences in V_1/2 curves between different β₁ subunits were tested by ANOVA with repeated measurements. P = 0.002 for β_1WT vs. β_1E65K, and P = 0.005 for β_1WT vs. α+β_1WT+β_1E65K.