Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension
J. Clin. Invest. José M. Fernández-Fernández, et al. 113:1032 doi:10.1172/JCI20347 [Go to this article.]

Figure 1
(A) E65K genotype distribution by DBP. P values for genotype distributions at each level of diastolic hypertension are shown (with the number of subjects in parentheses). (B) Age- and sex-adjusted ORs at each level of diastolic hypertension are presented for K-carriers versus EE genotype. The adjusted ORs for K-carriers of DBP ≥ 105 mmHg and DBP ≥ 110 mmHg were 0.39 (95% confidence interval, 0.17–0.93, P = 0.034) and 0.12 (95% confidence interval, 0.02–0.90, P = 0.039), respectively. *Subjects under hypertension treatment with DBP < 90 mmHg were also included in this group.