LE T cells responded to CDR, but not to FWR, peptides. (A and B) T cells were cultured with irradiated autologous PBMCs (A) or irradiated EBV-583 cells (B) in the absence or presence of 20 ∝M LE-CDR2-1 or LE-CDR3. An equal amount of TL-CDR3 peptide was used as a specificity control. (C) LE-1 T cells were cultured with irradiated EBV-583 cells in the absence or presence of different doses (0.8_100 ∝M) of LE-CDR2 and -FWR peptides, as indicated. The proliferation response (cpm or Ø cpm) from a representative experiment is shown.