The IL-12Rβ2 gene functions as a tumor suppressor in human B cell malignancies
J. Clin. Invest. Irma Airoldi, et al. 113:1651 doi:10.1172/JCI20303 [Go to this article.]

Figure 6
Assessment of proliferation and apoptosis of IL-12Rβ2_transfected Raji (A) and RPMI 8866 (B) cells following incubation with hrIL-12. (A and B, left panel) cells were cultured with hrIL-12 for 24 to 96 hours and counted by an electronic counter. One representative experiment out of the five performed is shown. (A and B, middle panel) [H3]-thymidine incorporation by cells incubated with hrIL-12 for 72 hour. The means ± SD from five independent experiments are shown. Results are expressed as cpm (A and B, right panel). Cells were cultured with hrIL-12 for 5 to 96 hours and tested for apoptosis by the TUNEL assay. The means ± SD from three independent experiments are shown. Results are expressed as percent apoptotic cells.