Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
J. Clin. Invest. Donna Woulfe, et al. 113:441 doi:10.1172/JCI20267 [Go to this article.]

Figure 5
Thrombotic response of mice to ferric chloride injury of the carotid artery. Flow rates were measured in the carotid artery following exposure to FeCl₃. (a) For each genotype, the number of mice forming a stable occlusion (flow rate = 0.1 ml/min) that did not dislodge during the 30-minute time interval are shown in black. The number of mice that formed a transient occlusion that resolved (rate = 0.2 ml/min) is shown in gray, and the number of mice whose arteries remained patent throughout the period of observation is shown in white. (b) Representative flow traces for each genotype.