Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
J. Clin. Invest. Donna Woulfe, et al. 113:441 doi:10.1172/JCI20267 [
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Figure 4Fibrinogen binding in WT versus Akt-deficient platelets. Washed human platelets were treated with buffer alone (thin black line), 250 μM AYPGQV (heavy black line), or 500 μM AYPGQV (light gray line) as described in Figure
3b but stained with FITC-labeled mouse fibrinogen (100 μg/ml). The results shown are representative of three experiments.