Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport
J. Clin. Invest. Fatima Ferreirinha, et al. 113:231 doi:10.1172/JCI20138 [
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Figure 4Muscular phenotype in paraplegin-deficient mice. H&E and cytochrome
c oxidase staining of the skeletal muscle of a control (
a and
c) and a knockout mouse (
b and
d) at 13.5 months showing fiber hypotrophy, splitting, angulated fibers, central nuclei (
b), and targetoid cores (
d) in
Spg7–/– mice.