Rakesh K. Jain, Michael F. Booth
J Clin Invest.
2003;
112(8):1134–1136
doi:10.1172/JCI20087
This article Copyright © 2003, The American Society for Clinical Investigation
Abstract
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P
aracrine signaling via platelet-derived growth factor B (PDGFB), expressed by endothelial cells, and its receptor PDGFR-β, expressed by pericytes, plays a central role in blood vessel maturation. A new study reveals that it is not just the presence of PDGFB, but how it is presented to pericytes, that determines the quality of the endothelium-pericyte interaction.
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