Selectin and selectin ligand binding: a bittersweet attraction
J. Clin. Invest. Thomas M. Zollner, et al. 112:980 doi:10.1172/JCI19962 [
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Figure 2(
a) Biosynthesis of core 2–type, sLe
X-containing
O-glycans. sLe
X is circled. (
b) In the presence of 4-F-GlcNAc, the inhibitor is incorporated into poly-
N-acetyllactosamine chains, which finally leads to termination of chain elongation.
