Jordan S. Orange, Raif S. Geha
J Clin Invest.
2003;
112(7):983–985
doi:10.1172/JCI19960
This article Copyright © 2003, The American Society for Clinical Investigation
Abstract
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T
he pathways between a receptor and transcriptional activation mediated by NF-κB are complex. The study of human gene mutations that result in dysregulation of these pathways has provided insight into the functions of individual components of the pathway, their interrelations, and the significance of these systems to the organism .
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