PPAR γ insufficiency enhances osteogenesis through osteoblast formation
from bone marrow progenitors
J. Clin. Invest. Toru Akune, et al. 113:846 doi:10.1172/JCI19900 [
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Figure 4Radiological and histomorphometric analyses of OVX and sham-operated (Sham) female littermates of
PPARγ+/– and WT genotypes. Female mice underwent surgical operation at 26 weeks and were analyzed at 30 weeks of age. (A) Plain x-ray images of femora and tibiae (left) and three-dimensional CT images of distal femora (right) of representative mice. (B) Histomorphometric parameters. Data are expressed as means (bars) ± SEMs (error bars) for eight mice per group for
PPARγ+/– and WT mice. *Significant difference from WT,
P < 0.01.
#Significant difference from sham,
P < 0.05.
