Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses
J. Clin. Invest. Akira Yamaguchi, et al. 113:200 doi:10.1172/JCI19639 [Go to this article.]

Figure 7
Reduction in the neurodegeneration of Purkinje cells in Hexb^–/–FcRγ^–/– mice and 14-week-old Hexb^–/–FcRγ^+/+ mice, but not Hexb^–/–FcRγ^–/– or Hexb^+/+FcRγ^+/+, displayed neurodegeneration and shrinkage of nuclei in Purkinje cells. Arrows indicate nuclei of Purkinje cells. H&E stain, original magnification, ×100. PI stain, original magnification, ×600. ML, molecular layer, Pc, Purkinje cells, GL, granular layer.