Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses
J. Clin. Invest. Akira Yamaguchi, et al. 113:200 doi:10.1172/JCI19639 [
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Figure 1Detection of anti-GM2 and-GA2 antibodies, IL-4 and INF-γ by ELISA. Autoantibodies against GM2 (
a) and GA2 (
b) in serum were measured in
Hexb–/– (squares) and
Hexb+/+ (diamonds) mice. Serum IL-4 (
c) and INF-γ (
d) levels were measured in 14-week-old
Hexb–/– and
Hexb+/+ mice.
n = eight mice per group. *
P < 0.01, Student’s
t test.