A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression
J. Clin. Invest. Janete M. Cerutti, et al. 113:1234 doi:10.1172/JCI19617 [
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Figure 1Relative levels of expression determined by quantitative RT-PCR in 23 samples of FTA and FTC (black bars) and in normal thyroid tissues (gray bars). Transcript levels were normalized to the average of ribosomal protein 8 and t-complex 1, which were uniformly expressed in all three thyroid SAGE libraries. Numbers 1–10 correspond to FTA and 11–23 to FTC cases described in Table
2. The statistical analysis of RT-PCR values revealed that expression of the genes
DDIT3,
ARG2, and
ITM1 was significantly different at the 0.05 level, and expression of
C1orf24 was significant at the 0.10 level.
