Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness
J. Clin. Invest. Scott S. Wagers, et al. 114:104 doi:10.1172/JCI19569 [
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Figure 7Concentrations of fibrin degradation products (D-dimer) in the BAL fluid of mice that had been exposed to aerosolized tPA. The concentration of D-dimer increased significantly in the BAL from mice with airway inflammation exposed to tPA (
n = 9) compared with those exposed to saline (
n = 8, 17.8 ± 2.7 ng/ml compared with 9.05 ± 0.6 ng/ml).
