Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness
J. Clin. Invest. Scott S. Wagers, et al. 114:104 doi:10.1172/JCI19569 [Go to this article.]

Figure 2
PAI activity in lung tissue homogenates of mice with airway inflammation. PAI activity with respect to protein content was significantly increased in mice with allergic airway inflammation (n = 9) compared with controls (n = 9): 2.34 ± 0.3 AU/μg compared with 0.12 ± 0.1 AU/μg, P < 0.01. A concurrent decrease in PA activity was observed in mice with allergic airway inflammation compared with controls: 9.28 ± 0.4 AU/μg compared with 4.6 ± 0.4 AU/μg, P < 0.01.