Niels C. Riedemann, Ren-Feng Guo, Peter A. Ward
J Clin Invest.
2003;
112(4):460–467
doi:10.1172/JCI19523
This article Copyright © 2003, The American Society for Clinical Investigation
Abstract
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S
epsis remains a serious cause of morbidity and mortality, and the pathophysiology of the disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving. This review discusses the search for effective therapeutic interventions, hurdles in translational sepsis research, and new therapies in development in current clinical trials.
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