Thyroid hormone action: a binding contract
J. Clin. Invest. Mitchell A. Lazar, et al. 112:497 doi:10.1172/JCI19479 [Go to this article.]

Figure 1
Paradigm for positive regulation of gene expression by TH. TH binding to TR triggers a switch from corepressor (CoR) to coactivator (CoA) binding on a TRE on DNA.