Amyloid β and Alzheimer disease therapeutics: the devil may be in the details
J. Clin. Invest. John R. Cirrito, et al. 112:321 doi:10.1172/JCI19420 [
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Figure 1Model of how certain NSAIDs decrease Aβ42 production. NSAIDs may directly bind to the γ-secretase complex and alter APP processing to decrease Aβ42 production and also change production of other Aβ species.
