PKCβ regulates ischemia/reperfusion injury in the lung
J. Clin. Invest. Tomoyuki Fujita, et al. 113:1615 doi:10.1172/JCI19225 [
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Figure 2I/R-mediated activation of PKCβII in the lung.
PKCβ
+/+ and
PKCβ
–/– mice were subjected to left-lung ischemia for 1 hour and reperfusion for 10–15 minutes. Membranous fractions were prepared from I/R and uninstrumented lung, and were subjected to SDS-PAGE (7.5%, 5 ∝g of total protein/lane) and immunoblotting with antibody to PKCβII (
A), PKCδ (
B), and PKCε (
C).