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Ellen M. Gravallese
J Clin Invest. 2003;
112(2):147
doi:10.1172/JCI19190
Abstract |
Full text
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T
he molecular mechanisms underlying the putative role of osteopontin in the chronic inflammatory disease rheumatoid arthritis are unclear. A study in a murine model of arthritis now demonstrates that a specific antibody directed against the exposed osteopontin epitope SLAYGLR is capable of preventing inflammatory cell infiltration in arthritic joints.
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(18)
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