Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
J. Clin. Invest. Håkan Björne, et al. 113:106 doi:10.1172/JCI19019 [
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Figure 4Maximum mucosal blood flow responses (upper panel,
n = 7–13 rats) after topical application of human saliva or sodium nitrite (0.1–5 mM) to the gastric mucosa in relation to generation of NO (lower graphs,
n = 5). Saliva or sodium nitrite solutions were mixed with HCl to pH 2. Final nitrite levels were 0.23 μM in experiments with fasting saliva and 1.1 mM when using saliva collected after a nitrate load. Values are expressed as mean ± SEM. *
P < 0.01 compared with baseline.
