Methylguanine methyltransferase–mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model
J. Clin. Invest. Tobias Neff, et al. 112:1581 doi:10.1172/JCI18782 [Go to this article.]

Figure 5
Protection of multiple stem cell clones. LAM-PCR-analysis of DNA derived from peripheral blood and bone marrow from dog G154 demonstrates multiple different clones that persist after in vivo selection. Before, before any selection; after, after any selection. Lanes 1–7: peripheral blood samples from day 53 (before, lane 1), day 76 (before, lane 2), day 165 (after, lane 3), day 173 (after, lane 4), day 236 (after, lane 5), day 259 (after, lane 6), day 284 (after, lane 7). Lanes 8–10: bone marrow samples from day 76 (before, lane 8), day 175 (after, lane 9), day 259 (after, lane 10). Lane 11: DNA from a normal dog used as negative control. Day 0 is the day of transplantation.