Methylguanine methyltransferase–mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model
J. Clin. Invest. Tobias Neff, et al. 112:1581 doi:10.1172/JCI18782 [
Go to this article.]
Figure 4Conversion to full donor chimerism mediated by in vivo selection. VNTR analysis demonstrates an increase in donor contribution from approximately 55% to greater than 95% after in vivo selection. PB, DNA isolated from peripheral blood total nucleated cells; BM, DNA isolated from bone marrow total nucleated cells.
