JCI - Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor

Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice
J. Clin. Invest. 112:8 doi:10.1172/JCI18580 [Go to this article.]

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Figure 2

Atherosclerosis in IKK2^fl- and IKK2^del-transplanted Ldlr^–/– mice. (a) Representative lesions from Ldlr^–/– mice transplanted with IKK2^fl and (b) IKK2^del BMM using MOMA-2. (c) Atherosclerotic lesion area in IKK2^fl-transplanted (open circles, n = 20) and IKK2^del-transplanted (closed circles, n = 18) Ldlr^–/– mice. Circles indicate individual mice. *P < 0.01.