The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
J. Clin. Invest. Daniela Cota, et al. 112:423 doi:10.1172/JCI17725 [Go to this article.]

Figure 3
CB1 transcripts are co-localized with mRNAs of hypothalamic neuropeptides. Bright field micrographs. Vector Red staining, CB1; silver grains, neuropeptides. (a) Co-localization of CB1 and CRH mRNA in PVN. (b) Co-localization of CB1 and CART mRNA in PVN. (c) Co-localization of CB1 and prepro-orexin mRNA in LHA. (d) Co-localization of CB1 and MCH mRNA in LHA. Filled arrow, cell coexpressing CB1 and the respective neuropeptide; open arrow, cell expressing only the respective neuropeptide; asterisk, cell expressing only CB1 mRNA. Scale bars, 10 μm.