Prevention of gastrointestinal tumors based on adenomatous polyposis coli gene mutation by dendritic cell vaccine
J. Clin. Invest. Toshio Iinuma, et al. 113:1307 doi:10.1172/JCI17323 [Go to this article.]

Figure 7
Effect of administration of anti-CD4 mAb’s or anti-CD8 mAb’s on the antitumor effect induced by DC/Ts. Anti-mouse CD4 mAb’s or anti-mouse CD8 mAb’s were administered at a dose of 0.5 mg/mouse intraperitoneally, 1 day before and 2 days after each of the DC/T inoculations; these mice were treated with IL-12 and sacrificed at 10 weeks of age as described in the text. The tumors in the gastrointestinal tracts were counted as described in the legend for Figure 3. Each column represents mean ± SD (error bar) of the number of tumors (n = 3). *P < 0.01; **P < 0.001.