Prevention of gastrointestinal tumors based on adenomatous polyposis coli gene mutation by dendritic cell vaccine
J. Clin. Invest. Toshio Iinuma, et al. 113:1307 doi:10.1172/JCI17323 [Go to this article.]

Figure 2
Macroscopic view of the upper ilei of APC1309 mice. The entire gastrointestinal tracts of 10-week-old mice were processed as described in the text. The upper ilei were excised and are shown here. The tumors are identified as black dots on the mucosa. The arrow indicates a stenotic change of the intestine by tumor growth in an untreated mouse. (A) Upper ileum from an untreated mouse (B) from a mouse treated with DC/Ts, and (C) from a mouse treated with DC/T + IL-12.