Genetic disruption of γ-melanocyte–stimulating hormone signaling leads to salt-sensitive hypertension in the mouse
J. Clin. Invest. Xi-Ping Ni, et al. 111:1251 doi:10.1172/JCI16993 [
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Figure 1Representative gels showing PCR amplification products for targeted deletions of (
a)
PC2, (
b)
Mc3r, and (
c)
Mc4r genes as described in Methods. +/+, wild type; +/–, heterozygous; –/–, homozygous knockout. Left column is size ladder; 500 indicates 500 bp.