Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability
J. Clin. Invest. Huixing Wu, et al. 111:1589
doi:10.1172/JCI16889 [Go to this article.]

Figure 1
Modulation of E. coli clearance from the lungs of pulmonary collectin mouse models. Bacterial CFUs in lung homogenates were quantified 6 hours after intratracheal inoculation with 5 × 106 E. coli in age- and inbred strain–matched SP-A–/– and SP-A+/+ C3H/HeN mice, or Swiss Black SP-D–overexpressing mice (+/+, rSP-D) and littermate controls (+/+). Data are mean ± SEM; n = 10 per group; *P < 0.05.