Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs
J. Clin. Invest. Graciela Andonegui, et al. 111:1011 doi:10.1172/JCI16510 [Go to this article.]

Figure 3
Circulating neutrophils exposed to LPS in vivo exhibit a state of activation. TLR4^+/+ mice were treated with or without LPS for 4 hours, and then whole blood was drawn by cardiac puncture. Neutrophil L-selectin and CD11b expression were assessed by flow cytometric analysis. Results are shown as the MCF ± SEM for untreated (white bars) and LPS-treated (black bars) mice (n = 3 per group). *P < 0.05 vs. untreated mice.