Release and movement of lipid-modified Hh. Secretion of N-Hh^chol (with palmitoylation) requires the action of Disp, possibly to override the affinity of the lipid anchors to the membrane. Hexamerization of the ligand may facilitate this process by hiding the lipids inside the complex. Once released, N-Hh^chol moves from one cell to another in a process dependent on HSPG whose synthesis requires Ttv. Ptc and Hip limit Hh diffusion by sequestering the ligand.