Sensitizing antigen-specific CD8+ T cells for accelerated suicide causes immune incompetence
J. Clin. Invest. Christoph Wasem, et al. 111:1191 doi:10.1172/JCI16344 [
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Figure 5Uncontrolled viral replication in Bis VIII–treated animals. Animals were infected with LCMV and treated with PBS (white bars) or Bis VIII (black bars) as described in Methods. On day 7 after infection, sera and samples from spleen, liver, and small intestine were collected, and levels of infectious virus particles were determined by plaque assay. Two typical experiments of nine performed are shown. An asterisk indicates viral particles below the detection limit (10
3 per gram of tissue or milliliter of serum).
