Endothelial lipase is a major determinant of HDL level
J. Clin. Invest. Tatsuro Ishida, et al. 111:347 doi:10.1172/JCI16306 [
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Figure 3Cholesterol levels in lipoprotein fractions obtained by FPLC. Determination of cholesterol concentration in serum fractions obtained by FPLC revealed a correlation between
LIPG genotype and HDL cholesterol levels. HDL cholesterol levels for
LIPG–/– mice were significantly greater than for wild-type mice in fractions 28 and 29 (
P < 0.05). HDL cholesterol levels were lower in
LIPG transgenic animals for fractions 29 and 30 (
P < 0.05) than in wild-type mice. KO,
LIPG–/–; Tg, h
LIPGTg.*
P < 0.05 vs. WT.
