Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
J. Clin. Invest. Julian J. Lum, et al. 111:1547 doi:10.1172/JCI16233 [Go to this article.]

Figure 7
Effect of wild-type or R77Q Vpr on isolated mitochondria. Mitochondria were isolated and treated with the indicated concentration of wild-type Vpr or R77Q Vpr, and supernatants were analyzed for cytochrome c release. Equal loading of protein was confirmed using PCNA, and purity was assessed by Hsp70 immunoblots (data not shown).