Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
J. Clin. Invest. Julian J. Lum, et al. 111:1547 doi:10.1172/JCI16233 [Go to this article.]

Figure 2
Vpr R77Q induces less apoptosis than wild-type Vpr. Jurkat cells were treated with synthetic C-terminal wild-type or R77Q Vpr peptides for 16 hours followed by annexin V FITC/propidium iodide staining. Data represent the average of three independent experiments. The inset denotes the number of propidium iodide–positive cells at each time point.