Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation
J. Clin. Invest. Paul J. Egan, et al. 111:915 doi:10.1172/JCI16156 [
Go to this article.]
Figure 4Histological assessment of acute inflammatory arthritis in
SOCS-1+/+ IFN-γ–/– and
SOCS-1–/– IFN-γ–/– mice. Joint sections were graded for five features of inflammatory arthritis, each on a scale of 0 (normal) to 5 (severe). Mice were sacrificed on day 7 (
a) or day 14 (
b) after mBSA injection. Results shown are the mean + SEM of ten knee joints and are representative of three independent experiments. *
P < 0.005,
†P < 0.01 by Mann-Whitney test.
