Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
J. Clin. Invest. M. Llanos Casanova, et al. 111:43 doi:10.1172/JCI16116 [Go to this article.]

Figure 1
Western blot analysis of cannabinoid receptor expression in normal skin and skin tumors. (a) CB₁ and CB₂ receptor expression in murine and human epidermal cell lines, normal skin, and skin tumors. (b) Controls with the anti-CB₁ or anti-CB₂ Ab-blocking peptide are shown (see Methods and Results for explanation). Mouse papillomas were generated by chemical carcinogenesis (as described in ref. 9), while mouse squamous cell carcinomas (SCCs) were generated by inoculation of PDV.C57 epidermal tumor cells as described in Methods. The source of human samples is described in Methods. Images of representative samples are shown. Similar results were obtained in at least two other blots. PB, immortalized mouse nontumorigenic cell line derived from SENCAR mice papillomas; HK, human keratinocytes; m, mouse; h, human.