Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay-accelerating factor protection
J. Clin. Invest. Feng Lin, et al. 110:1269 doi:10.1172/JCI16086 [
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Figure 4Diaphragm muscles from the
Daf1–/– (
a and
b) and
Daf1+/+ (
c and
d) mice 48 hours after injection with McAb-3 mAb. αBTX stain demonstrates the endplate regions (
a and
c). Double-labeling with FITC-labeled anti-C3 Ab (1:3,000 dilution) demonstrates C3 deposition at almost all junctions from the
Daf1–/– animal (
b), while no complement deposition is observed in junctions of muscles from the
Daf1+/+ animal. Scale bar = 100 μm.
