Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo
J. Clin. Invest. Sydney Tang, et al. 111:515 doi:10.1172/JCI16079 [Go to this article.]

Figure 8
Effect of exogenous H₂O₂, or albumin with PI3K or PKC inhibitors on NF-κB activation in PTECs. EMSA was performed with nuclear extracts of PTECs treated for 1 h with medium alone (control), H₂O₂ (200 μM), HSA (10 mg/ml), LY294002 (100 μM, added 1 h before the addition of HSA), wortmannin (500 nM, added 1 h before the addition of HSA), GF109203X (5 μM, added 1 h before the addition of HSA), or staurosporin (100 nM, added 1 h before the addition of HSA). The results shown are representative of three independent experiments.