Mechanisms of TNF-α– and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
J. Clin. Invest. Christopher T. Ritchlin, et al. 111:821 doi:10.1172/JCI16069 [Go to this article.]

Figure 8
RANK, RANKL, and OPG expression in PsA synovium. Total RNA was isolated from PsA and OA synovium and used as the template to determine RANK, RANKL, and OPG mRNA expression by RT-PCR as described in Methods. The sizes of the specific PCR products are indicated. Lanes 1–5 show PsA patients with radiographic bone erosions, lane 6 shows a patient without erosions, and lanes 7 and 8 show OA patients.