Mechanisms of TNF-α– and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
J. Clin. Invest. Christopher T. Ritchlin, et al. 111:821 doi:10.1172/JCI16069 [
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Figure 2OCPs in PBMCs of PsA patients. PBMCs were obtained from PsA patients and healthy controls and cultured in the absence (
a and
b) or presence (
c and
d) of MCSF (25 ng/ml) and RANKL (100 ng/ml) for 14 days, fixed and stained for TRAP, and photographed at ×10 magnification. Numbers in parentheses represent the total number of osteoclasts per 10
6 PBMCs for each sample.