Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway
J. Clin. Invest. Jennifer L. Gommerman, et al. 110:1359 doi:10.1172/JCI15975 [
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Figure 4FDC network areas in the spleen are significantly diminished following treatment with LTβR-Ig in all dose groups. Spleen sections stained with anti-CD35 Ab’s were subjected to morphometric analysis. FDC networks in the spleen (
a and
c) and LN (
b) were quantified in terms of areas compared with overall tissue area. For D29 (day 29) data, 8-mg/kg intravenous and subcutaneous groups were combined. For recovery data (
c), all doses were combined.